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Waters Corporation manufactures analytical instruments worldwide. It designs, manufactures, and sells high performance liquid chromatography (HPLC) instruments, ultra performance liquid chromatography and mass spectrometry (MS) instrument systems, and associated service and support products, including chromatography columns and other consumable products. The company's LC instruments are used to detect, identify, monitor, and measure the chemical, physical, and biological composition of materials. Its MS instruments are used in drug discovery and development, including clinical trial testing, analysis of proteins in disease processes, food safety analyses, and environmental testing. Waters also offers thermal analysis and rheometry instruments, which are used in predicting the suitability of polymers and viscous liquids for various industrial, consumer goods, and health care products. In addition, the company offers laboratory-to-enterprise scale software systems for managing and storing scientific information collected from various instrumental test methods. The company offers its products to pharmaceutical companies, generic drug manufacturers, biotechnology companies, chemical manufacturers, polymer manufacturers, food and beverage companies, environmental testing laboratories, universities, and government agencies. Waters was founded by James L. Waters in 1958 and is headquartered in Milford, Massachusetts.